Jentin 50MG Tablets

Product Description

SPECIFICATION

Generics : Sitagliptin

Used For : Diabetes

How it works : Sitagliptin is a DPP-4 inhibitor, which is believed to exert its actions in patients with type 2 diabetes by slowing the inactivation of incretin hormones, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). The incretins are part of an endogenous system involved in the physiologic regulation of glucose homeostasis. When blood glucose concentrations are normal or elevated, GLP-1 and GIP increase insulin synthesis and release from pancreatic beta cells by intracellular signaling pathways involving cyclicAMP. GLP1 also lowers glucagon secretion from pancreatic alpha cells, leading to reduced hepatic glucose production. By increasing and prolonging active incretin levels, sitagliptin increases insulin release and decreases glucagon levels in the circulation in a glucose-dependent manner.

USAGE AND SAFETY

Dosage : Sitagliptin

Side Effects : Upper respiratory-tract infections, headache and nasopharyngitis.

ADDITIONAL INFORMATION

Pregnancy category : Always consult your physician before using any medicine.