Product Description
SPECIFICATION
Generics : Amitriptyline HCl
Used For : Depression
How it works : Amitriptyline is a tricyclic antidepressant and an analgesic. It has marked anticholinergic and sedative properties. It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity. The mechanism of action also includes ion-channel blocking effects on sodium, potassium and NMDA channel at both central and spinal cord level. The noradrenaline, sodium and the NMDA effects are mechanisms known to be involved in the maintenance of neuropathic pain, chronic tension type headache prophylaxis and migraine prophylaxis. The pain-reducing effect of amitriptyline is not linked to its anti-depressive properties.
USAGE AND SAFETY
Dosage : Amitriptyline HCl
Side Effects : Very common (may affect more than 1 in 10 people): • Sleepiness/drowsiness • Shakiness of hands or other body parts • Dizziness, headache, dizziness when you stand up due to low blood pressure (orthostatic hypotension) • Irregular, hard, or rapid heartbeat • Dry mouth, constipation, nausea • Excessive sweating • Weight gain • Slurred or slow speech • Aggression • Congested nose. Common: (may affect up to 1 in 10 people): • Confusion • sexual disturbances (decreased sex-drive, problems with erection) • disturbance in attention • changes in taste • numbness or tingling in the arms or legs • disturbed coordination • dilated pupils • heart block • fatigue
ADDITIONAL INFORMATION
Pregnancy category : Always consult your physician before using any medicine.
Storage (YES/NO) : Store this medicine at room temperature, away from direct light and heat
Dose | 25mg |
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